Super Size Me, the popular documentary film about the health effects of a massive fast-food diet, has an official game. It looks like it was a promotion for the DVD release, so it must have been around for a while already. (thanks to Nico)

It's cute and has good production value, but it's essentially a Pac Man clone. And if I'm going to criticize other clones, then I'm sort of obliged to give the same treatment here. The subject of healthcare and diet is a great subject for a game, because a game can show change over time, and furthermore a game can accelerate time to show the long term effects of short term behavior.